Bed Bug control for luggage is the best way to protect your luggage from infestation. What you will do is, open your luggage and any zippers you may have on your luggage and spray it down the best you can. You will want to spray the seams and any closed area inside and outside you luggage. You should also spray down your handle and wheels (if available). Bed bug control will keep the germs from different hotels or any where you travel, so that it doesn't follow you back home.